[HTML][HTML] The case for an adverse interaction between aspirin and non-steroidal anti-inflammatory drugs: is it time to believe the hype?

JP Curtis, HM Krumholz - Journal of the American College of Cardiology, 2004 - jacc.org
JP Curtis, HM Krumholz
Journal of the American College of Cardiology, 2004jacc.org
Twice in the past year, headlines across the nation have highlighted the publication of
studies suggesting that nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit the
cardioprotective effects of aspirin (1, 2). Based on these results, some experts have strongly
recommended that patients avoid taking these medications in combination (3, 4). These
studies and the resultant publicity place clinicians in an uncomfortable position and raise the
natural question whether the current evidence supports this degree of concern.
Twice in the past year, headlines across the nation have highlighted the publication of studies suggesting that nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit the cardioprotective effects of aspirin (1, 2). Based on these results, some experts have strongly recommended that patients avoid taking these medications in combination (3, 4). These studies and the resultant publicity place clinicians in an uncomfortable position and raise the natural question whether the current evidence supports this degree of concern.
jacc.org