CD4 T-lymphocyte recovery in individuals with advanced HIV-1 infection receiving potent antiretroviral therapy for 4 years: the Swiss HIV Cohort Study

GR Kaufmann, L Perrin, G Pantaleo… - Archives of internal …, 2003 - jamanetwork.com
Background Highly active antiretroviral therapy (HAART) for human immunodeficiency virus
(HIV)-1 infection allows recovery of CD4 T lymphocytes. Few studies have explored the long-
term T-lymphocyte responses to HAART. Methods Plasma HIV-1 RNA levels and CD4 and
CD8 T-lymphocyte counts were longitudinally analyzed over 4 years in 2235 participants of
the Swiss HIV Cohort, commencing HAART between 1996 and 1997. The CD4 T-
lymphocyte count increase, the percentage of individuals with a CD4 T-lymphocyte count of …