Nonthyroidal illness syndrome: evaluation of thyroid function in sick patients
JE Langton, GA Brent - Endocrinology and Metabolism Clinics, 2002 - endo.theclinics.com
Nonthyroidal illness influences thyroid hormone production and action at multiple levels,
including the hypothalamic–pituitary–thyroid (HPT) axis, thyroid hormone transport, and
metabolism [10, 15, 19, 38, 64]. These changes in thyroid function in the setting of systemic
illness, surgery, or fasting are referred to as the nonthyroidal illness syndrome (also called
''sick euthyroid syndrome''). Evaluation of thyroid status is challenging in sick patients
because of alteration in thyroid function tests and the unreliability of clinical assessment in …
including the hypothalamic–pituitary–thyroid (HPT) axis, thyroid hormone transport, and
metabolism [10, 15, 19, 38, 64]. These changes in thyroid function in the setting of systemic
illness, surgery, or fasting are referred to as the nonthyroidal illness syndrome (also called
''sick euthyroid syndrome''). Evaluation of thyroid status is challenging in sick patients
because of alteration in thyroid function tests and the unreliability of clinical assessment in …