Serum proteomic profiling can discriminate prostate cancer from benign prostates in men with total prostate specific antigen levels between 2.5 and 15.0 ng/ml
DK Ornstein, W Rayford, VA Fusaro, TP Conrads… - The Journal of …, 2004 - Elsevier
PURPOSE: Artificial intelligence based pattern recognition algorithms have been developed
and successfully used to analyze complex serum proteomic data streams generated by
surface enhanced, laser desorption ionization time-of-flight mass spectroscopy. In the
current study we used a high performance, hybrid quadrupole time-of-flight mass
spectrometer to generate discriminatory serum proteomic profiles to determine if this
technology could be used to determine the need for prostate biopsy in men with elevated …
and successfully used to analyze complex serum proteomic data streams generated by
surface enhanced, laser desorption ionization time-of-flight mass spectroscopy. In the
current study we used a high performance, hybrid quadrupole time-of-flight mass
spectrometer to generate discriminatory serum proteomic profiles to determine if this
technology could be used to determine the need for prostate biopsy in men with elevated …