[HTML][HTML] Phosphorylation of αB-crystallin in response to various types of stress

H Ito, K Okamoto, H Nakayama, T Isobe… - Journal of Biological …, 1997 - ASBMB
Phosphorylation of αB-crystallin, a member of the hsp27 family, in human glioma (U373 MG)
cells was stimulated by exposure of the cells to various stimuli, which included heat,
arsenite, phorbol 12-myristate 13-acetate (PMA), okadaic acid, H 2 O 2, anisomycin, and
high concentrations of NaCl or sorbitol, but not in response to agents that elevated
intracellular levels of cyclic AMP. Cells exposed to PMA together with okadaic acid yielded
three bands of 32 P-labeled αB-crystallin when immunoprecipitated samples were subjected …