[HTML][HTML] Lipoprotein cholesteryl ester production, transfer, and output in vivo in humans
CC Schwartz, JM VandenBroek, PS Cooper - Journal of lipid research, 2004 - ASBMB
Our aim was to identify and quantify the major in vivo pathways of lipoprotein cholesteryl
ester transport in humans. Normal (n= 7), bile fistula (n= 5), and familial
hypercholesterolemia (FH; n= 1) subjects were studied. Each received isotopic free
cholesterol in HDL, LDL, or particulate form, along with another isotope of free or esterified
cholesterol or mevalonic acid. VLDL, intermediate density lipoprotein (IDL), LDL, HDL, blood
cells, and bile were collected for up to 6 days for analysis of radioactivity and mass of free …
ester transport in humans. Normal (n= 7), bile fistula (n= 5), and familial
hypercholesterolemia (FH; n= 1) subjects were studied. Each received isotopic free
cholesterol in HDL, LDL, or particulate form, along with another isotope of free or esterified
cholesterol or mevalonic acid. VLDL, intermediate density lipoprotein (IDL), LDL, HDL, blood
cells, and bile were collected for up to 6 days for analysis of radioactivity and mass of free …