Unique lipoprotein phenotype and genotype associated with exceptional longevity
N Barzilai, G Atzmon, C Schechter, EJ Schaefer… - Jama, 2003 - jamanetwork.com
ContextIndividuals with exceptional longevity have a lower incidence and/or significant
delay in the onset of age-related disease, and their family members may inherit biological
factors that modulate aging processes and disease susceptibility. ObjectiveTo identify
specific biological and genetic factors that are associated with or reliably define a human
longevity phenotype. Design, Setting, and ParticipantsIn a case-control design, 213
Ashkenazi Jewish probands with exceptional longevity (mean [SD] age, 98.2 [5.3] years) …
delay in the onset of age-related disease, and their family members may inherit biological
factors that modulate aging processes and disease susceptibility. ObjectiveTo identify
specific biological and genetic factors that are associated with or reliably define a human
longevity phenotype. Design, Setting, and ParticipantsIn a case-control design, 213
Ashkenazi Jewish probands with exceptional longevity (mean [SD] age, 98.2 [5.3] years) …