Several HDL binding proteins, quite disparate in structure, have recently been cloned and
their role in HDL metabolism is currently being assessed. High density lipoprotein binding
protein, HBP (vigilin), which lacks a transmembrane domain is responsive to cell cholesterol
levels, but its physiological significance remains unknown. On the other hand much is
known about SR-B1, a member of the class B scavenger receptors. The level of SR-B1
expression correlates with both the selective transfer of cholesteryl ester into cells and …