Adrenomedullin, calcitonin gene-related peptide and their receptors: evidence for a decreased placental mRNA content in preeclampsia and HELLP syndrome
I Knerr, C Dachert, E Beinder, M Metzler… - European Journal of …, 2002 - Elsevier
Objective: The human placenta expresses a variety of vasoactive substances and
neuropeptides, which play an important role in the regulation of placental blood flow in both
the maternal and foetal compartment and are therefore of critical importance for foetal
growth and development. Our study was planned to examine placental mRNA amounts of
vasodilatory adrenomedullin (AM), calcitonin gene-related peptide (CGRP) and their
receptors (AM-R and CGRP-R) in preeclampsia and HELLP syndrome (hemolysis, elevated …
neuropeptides, which play an important role in the regulation of placental blood flow in both
the maternal and foetal compartment and are therefore of critical importance for foetal
growth and development. Our study was planned to examine placental mRNA amounts of
vasodilatory adrenomedullin (AM), calcitonin gene-related peptide (CGRP) and their
receptors (AM-R and CGRP-R) in preeclampsia and HELLP syndrome (hemolysis, elevated …