Bone structure, composition, and mineralization.
AL Boskey, AS Posner - The Orthopedic clinics of North America, 1984 - europepmc.org
AL Boskey, AS Posner
The Orthopedic clinics of North America, 1984•europepmc.orgBone structure and function are dependent on complex interactions between cells, matrix,
cell-derived factors, and systemic factors. The deposition of mineral in bone, which enables
the skeleton to function properly, is described as a four-step process of matrix modification,
crystal nucleation, crystal growth, and remodeling. Insight into the function of bone
components in the mineralization process is provided by in vitro studies and analysis of
abnormal calcifications.
cell-derived factors, and systemic factors. The deposition of mineral in bone, which enables
the skeleton to function properly, is described as a four-step process of matrix modification,
crystal nucleation, crystal growth, and remodeling. Insight into the function of bone
components in the mineralization process is provided by in vitro studies and analysis of
abnormal calcifications.
Bone structure and function are dependent on complex interactions between cells, matrix, cell-derived factors, and systemic factors. The deposition of mineral in bone, which enables the skeleton to function properly, is described as a four-step process of matrix modification, crystal nucleation, crystal growth, and remodeling. Insight into the function of bone components in the mineralization process is provided by in vitro studies and analysis of abnormal calcifications.
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