Electrically evoked itch in humans
A Ikoma, H Handwerker, Y Miyachi, M Schmelz - Pain, 2005 - Elsevier
We compared itch sensations and axon reflex flare induced by transcutaneous electrical
(0.08–8ms, 2–200Hz) and chemical (histamine iontophoresis; 100μC) stimulation. Stimuli
were applied to non-lesional volar wrist skin in 20 healthy human subjects and 10 patients
with atopic dermatitis. Intensity of evoked itch and pain sensations were rated on a
numerical rating scale (NRS) of 0 (no sensation) to 10 (the maximum sensation imaginable).
The axon reflex erythema was measured by laser Doppler imager and areas of alloknesis …
(0.08–8ms, 2–200Hz) and chemical (histamine iontophoresis; 100μC) stimulation. Stimuli
were applied to non-lesional volar wrist skin in 20 healthy human subjects and 10 patients
with atopic dermatitis. Intensity of evoked itch and pain sensations were rated on a
numerical rating scale (NRS) of 0 (no sensation) to 10 (the maximum sensation imaginable).
The axon reflex erythema was measured by laser Doppler imager and areas of alloknesis …