Efficacy of gabapentin in the management of pruritus of unknown origin
PD Yesudian, NJE Wilson - Archives of dermatology, 2005 - jamanetwork.com
Generalized pruritus is a distressing symptom that can occur in several dermatologic and
systemic disorders. 1 Generalized pruritus of unknown origin is that which affects patients
without any underlying dermatologic or systemic disorder and is unassociated with rash. It
most commonly occurs in older patients and persists for long periods, from months to years.
In many cases, the itching may be due to reduced water content of the skin, without overt
dryness. Failure of the normal processing of the itching sensation along the course of central …
systemic disorders. 1 Generalized pruritus of unknown origin is that which affects patients
without any underlying dermatologic or systemic disorder and is unassociated with rash. It
most commonly occurs in older patients and persists for long periods, from months to years.
In many cases, the itching may be due to reduced water content of the skin, without overt
dryness. Failure of the normal processing of the itching sensation along the course of central …