New insights into cell responses involved in experimental autoimmune encephalomyelitis and multiple sclerosis

M El Behi, S Dubucquoi, D Lefranc, H Zéphir… - Immunology letters, 2005 - Elsevier
Animal models of autoimmune diseases such as experimental autoimmune
encephalomyelitis (EAE) are inflammatory demyelinating diseases which comprise a
heterogeneous group of disorders that affect the peripheral and central nervous systems.
EAE presents close similarities with multiple sclerosis (MS), a chronic inflammatory disease
affecting central nervous system (CNS) white matter. Many studies have shown EAE to be a
particularly useful animal model for the understanding of both the mechanisms of immune …