[HTML][HTML] Pro-angiogenic signaling by the endothelial presence of CEACAM1
N Kilic, L Oliveira-Ferrer, JH Wurmbach, S Loges… - Journal of Biological …, 2005 - ASBMB
Here, we demonstrate the expression of carcinoembryonic antigen-related cell adhesion
molecule-1 (CEACAM1) in angiogenic sprouts but not in large mother blood vessels within
tumor tissue. Correspondingly, only human microvascular endothelial cells involved in in
vitro tube formation exhibit CEACAM1. CEACAM1-overexpressing versus CEACAM1-
silenced human microvascular endothelial cells were used in migration and tube formation
assays. CEACAM1-overexpressing microvascular endothelial cells showed prolonged …
molecule-1 (CEACAM1) in angiogenic sprouts but not in large mother blood vessels within
tumor tissue. Correspondingly, only human microvascular endothelial cells involved in in
vitro tube formation exhibit CEACAM1. CEACAM1-overexpressing versus CEACAM1-
silenced human microvascular endothelial cells were used in migration and tube formation
assays. CEACAM1-overexpressing microvascular endothelial cells showed prolonged …