[HTML][HTML] Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity
A Tsuchida, T Yamauchi, Y Ito, Y Hada, T Maki… - Journal of Biological …, 2004 - ASBMB
Adiponectin/Acrp30 is a hormone secreted by adipocytes, which acts as an antidiabetic and
antiatherogenic adipokine. We reported previously that AdipoR1 and-R2 serve as receptors
for adiponectin and mediate increased fatty acid oxidation and glucose uptake by
adiponectin. In the present study, we examined the expression levels and roles of
AdipoR1/R2 in several physiological and pathophysiological states such as
fasting/refeeding, obesity, and insulin resistance. Here we show that the expression of …
antiatherogenic adipokine. We reported previously that AdipoR1 and-R2 serve as receptors
for adiponectin and mediate increased fatty acid oxidation and glucose uptake by
adiponectin. In the present study, we examined the expression levels and roles of
AdipoR1/R2 in several physiological and pathophysiological states such as
fasting/refeeding, obesity, and insulin resistance. Here we show that the expression of …