Metabolic syndrome vs Framingham Risk Score for prediction of coronary heart disease, stroke, and type 2 diabetes mellitus

SG Wannamethee, AG Shaper, L Lennon… - Archives of internal …, 2005 - jamanetwork.com
Background We sought to compare metabolic syndrome (MetS) with the Framingham Risk
Score (FRS) as predictors of coronary heart disease (CHD), stroke, and type 2 diabetes
mellitus (DM2) in middle-aged men. Methods A prospective study of 5128 men aged 40 to
59 years with no history of cardiovascular disease (CVD)(CHD or stroke) or DM2 drawn from
general practices in 24 British towns and observed for 20 years. Metabolic syndrome was
defined as the presence of 3 or more metabolic abnormalities based on modified National …