Insulin as a predictor of coronary heart disease: Interaction with apolipoprotein E phenotype A report from the Multiple Risk Factor Intervention Trial
TJ Orchard, J Eichner, LH Kuller, DJ Becker… - Annals of …, 1994 - Elsevier
The objective of this study was to examine whether fasting serum insulin is a predictor of
coronary heart disease in high-risk US men, and whether any such predictive role explains
the enhanced cardiovascular risk seen in subjects with the apolipoprotein (Apo) E 3 2
phenotype. This was a nested case-control study of participants in the Multiple Risk Factor
Intervention Trial. Ninety-four subjects who died from coronary heart disease (post-trial
follow-up) and 114 case patients with myocardial infarction (during trial) were compared to …
coronary heart disease in high-risk US men, and whether any such predictive role explains
the enhanced cardiovascular risk seen in subjects with the apolipoprotein (Apo) E 3 2
phenotype. This was a nested case-control study of participants in the Multiple Risk Factor
Intervention Trial. Ninety-four subjects who died from coronary heart disease (post-trial
follow-up) and 114 case patients with myocardial infarction (during trial) were compared to …