Metabolic effects of neuropeptide Y injected into the sulcal prefrontal cortex
IS McGregor, JA Menéndez, DM Atrens - Brain research bulletin, 1990 - Elsevier
The metabolic effects of 10, 39 and 156 pmol doses of neuropeptide Y (NPY) injected into
the sulcal prefrontal cortex (SPC) were investigated in an open-circuit calorimeter. The 39
pmol dose produced a large and long lasting increase in respiratory quotient indicating both
increased utilization of carbohydrate as an energy substrate and the synthesis of fat from
carbohydrate. The 10 and 39 pmol doses produced an inhibition of energy expenditure that
was still evident 24 hours following the 10, but not the 39 pmol, dose. These energy …
the sulcal prefrontal cortex (SPC) were investigated in an open-circuit calorimeter. The 39
pmol dose produced a large and long lasting increase in respiratory quotient indicating both
increased utilization of carbohydrate as an energy substrate and the synthesis of fat from
carbohydrate. The 10 and 39 pmol doses produced an inhibition of energy expenditure that
was still evident 24 hours following the 10, but not the 39 pmol, dose. These energy …