[HTML][HTML] A crucial role for exopolysaccharide modification in bacterial biofilm formation, immune evasion, and virulence

C Vuong, S Kocianova, JM Voyich, Y Yao… - Journal of Biological …, 2004 - ASBMB
Biofilms play an important role in many chronic bacterial infections. Production of an
extracellular mixture of sugar polymers called exopolysaccharide is characteristic and
critical for biofilm formation. However, there is limited information about the mechanisms
involved in the biosynthesis and modification of exopolysaccharide components and how
these processes influence bacterial pathogenesis. Staphylococcus epidermidis is an
important human pathogen that frequently causes persistent infections by biofilm formation …