Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a …
SA Shumaker, C Legault, SR Rapp, L Thal, RB Wallace… - Jama, 2003 - jamanetwork.com
ContextPostmenopausal women have a greater risk than men of developing Alzheimer
disease, but studies of the effects of estrogen therapy on Alzheimer disease have been
inconsistent. On July 8, 2002, the study drugs, estrogen plus progestin, in the Women's
Health Initiative (WHI) trial were discontinued because of certain increased health risks in
women receiving combined hormone therapy. ObjectiveTo evaluate the effect of estrogen
plus progestin on the incidence of dementia and mild cognitive impairment compared with …
disease, but studies of the effects of estrogen therapy on Alzheimer disease have been
inconsistent. On July 8, 2002, the study drugs, estrogen plus progestin, in the Women's
Health Initiative (WHI) trial were discontinued because of certain increased health risks in
women receiving combined hormone therapy. ObjectiveTo evaluate the effect of estrogen
plus progestin on the incidence of dementia and mild cognitive impairment compared with …