TRAIL and immunity: more than a license to kill tumor cells

N Corazza, G Brumatti, C Schaer, I Cima… - Cell death and …, 2004 - nature.com
N Corazza, G Brumatti, C Schaer, I Cima, C Wasem, T Brunner
Cell death and differentiation, 2004nature.com
The continuously growing family of structurally related proteins of the tumor necrosis factor
(TNF) family has received enormous scientific attention due to their important role in the
regulation of cell activation, survival, death and many other physiological and
pathophysiological events (reviewed in Locksley et al. 1). In this News and Commentary, we
will focus on the only recently recognized and appreciated role of TNF-related apoptosis-
inducing ligand (TRAIL) in regulating various physiological and pathophysiological …
The continuously growing family of structurally related proteins of the tumor necrosis factor (TNF) family has received enormous scientific attention due to their important role in the regulation of cell activation, survival, death and many other physiological and pathophysiological events (reviewed in Locksley et al. 1). In this News and Commentary, we will focus on the only recently recognized and appreciated role of TNF-related apoptosis-inducing ligand (TRAIL) in regulating various physiological and pathophysiological processes involving immune cells.
nature.com