Elevated C-reactive protein levels in overweight and obese adults

M Visser, LM Bouter, GM McQuillan, MH Wener… - Jama, 1999 - jamanetwork.com
ContextHuman adipose tissue expresses and releases the proinflammatory cytokine
interleukin 6, potentially inducing low-grade systemic inflammation in persons with excess
body fat. ObjectiveTo test whether overweight and obesity are associated with low-grade
systemic inflammation as measured by serum C-reactive protein (CRP) level. Design and
SettingThe Third National Health and Nutrition Examination Survey, representative of the US
population from 1988 to 1994. ParticipantsA total of 16,616 men and nonpregnant women …