Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy
RK Jain - Nature medicine, 2001 - nature.com
Nature medicine, 2001•nature.com
Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination
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Anti-angiogenic therapy was proposed in 1971 as a means to treat solid tumors and in 1976 as a method of cancer prevention. Here we propose that this form of therapy, judiciously applied, can normalize the tumor vasculature and improve the delivery of therapeutics.
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