Long-term reinnervation effects after sciatic nerve lesions in adult rats
J IJkema-Paassen, MF Meek… - Annals of Anatomy …, 2005 - Elsevier
Transection of the sciatic nerve in adult rats induces drastic changes in hindleg muscles.
Earlier, we demonstrated that the reinnervated soleus (SOL) muscle, 21 weeks after a
transection mainly contains type II fibers. This is in striking contrast to normal muscle, which
consists to 80% of type I muscle fibers. Also we observed 13.9% of the fibers to be
polyneurally innervated. The problem of the present study is whether these changes are
reversible after longer survival periods. Therefore, the SOL was studied 60 weeks after …
Earlier, we demonstrated that the reinnervated soleus (SOL) muscle, 21 weeks after a
transection mainly contains type II fibers. This is in striking contrast to normal muscle, which
consists to 80% of type I muscle fibers. Also we observed 13.9% of the fibers to be
polyneurally innervated. The problem of the present study is whether these changes are
reversible after longer survival periods. Therefore, the SOL was studied 60 weeks after …
