[HTML][HTML] Transcriptional activation of mouse mast cell protease-7 by activin and transforming growth factor-β is inhibited by microphthalmia-associated transcription …
M Funaba, T Ikeda, M Murakami, K Ogawa… - Journal of Biological …, 2003 - ASBMB
Previous studies have revealed that activin A and transforming growth factor-β 1 (TGF-β 1)
induced migration and morphological changes toward differentiation in bone marrow-
derived cultured mast cell progenitors (BMCMCs). Here we show up-regulation of mouse
mast cell protease-7 (mMCP-7), which is expressed in differentiated mast cells, by activin A
and TGF-β 1 in BMCMCs, and the molecular mechanism of the gene induction of mmcp-7.
Smad3, a signal mediator of the activin/TGF-β pathway, transcriptionally activated mmcp-7 …
induced migration and morphological changes toward differentiation in bone marrow-
derived cultured mast cell progenitors (BMCMCs). Here we show up-regulation of mouse
mast cell protease-7 (mMCP-7), which is expressed in differentiated mast cells, by activin A
and TGF-β 1 in BMCMCs, and the molecular mechanism of the gene induction of mmcp-7.
Smad3, a signal mediator of the activin/TGF-β pathway, transcriptionally activated mmcp-7 …