Circulating intercellular adhesion molecule-1 in patients with hepatocellular carcinoma before and after hepatic resection.
A Taketomi, K Takenaka, T Matsumata… - Hepato …, 1997 - europepmc.org
A Taketomi, K Takenaka, T Matsumata, M Shimada, H Higashi, K Shirabe, H Itasaka…
Hepato-gastroenterology, 1997•europepmc.orgResults A complete surgical resection of the tumor masses did not result in a significant
reduction of cICAM-1 levels. The levels of aminotransferase after hepatic resection in
patients with an increased level of cICAM-1 in the post operative period (n= 7) were much
higher than in patients with a decreased level of cICAM-1 (n= 11)(p< 0.05). The 1-, 2-and 3-
year disease free survival rates in the former group were 42.9%, 14.3% and 0%,
respectively, and those in the later group were 72.7%, 54.5% and 54.5%, respectively (p< …
reduction of cICAM-1 levels. The levels of aminotransferase after hepatic resection in
patients with an increased level of cICAM-1 in the post operative period (n= 7) were much
higher than in patients with a decreased level of cICAM-1 (n= 11)(p< 0.05). The 1-, 2-and 3-
year disease free survival rates in the former group were 42.9%, 14.3% and 0%,
respectively, and those in the later group were 72.7%, 54.5% and 54.5%, respectively (p< …
Results
A complete surgical resection of the tumor masses did not result in a significant reduction of cICAM-1 levels. The levels of aminotransferase after hepatic resection in patients with an increased level of cICAM-1 in the post operative period (n= 7) were much higher than in patients with a decreased level of cICAM-1 (n= 11)(p< 0.05). The 1-, 2-and 3-year disease free survival rates in the former group were 42.9%, 14.3% and 0%, respectively, and those in the later group were 72.7%, 54.5% and 54.5%, respectively (p< 0.05).
Conclusions
The enhancement of inflammation in the remnant liver tissue is related to intrahepatic recurrence after hepatic resection through adhesion molecules, such as cICAM-1.
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