[PDF][PDF] Phase I Study of Adoptive T-Cell Therapy Using Antigen-Specific CD8+ T Cells for the Treatment of Patients With Metastatic Melanoma
A Mackensen, N Meidenbauer, S Vogl… - Journal of Clinical …, 2006 - Citeseer
A Mackensen, N Meidenbauer, S Vogl, M Laumer, J Berger, R Andreesen
Journal of Clinical Oncology, 2006•CiteseerPurpose The adoptive transfer of in vitro generated tumor antigen-specific cytotoxic T
lymphocytes (CTL) provides a promising approach to the immunotherapy of cancer. A phase
I study was conducted to test the feasibility, safety, and survival of adoptively transferred
Melan-A–specific CTL lines in melanoma patients.
lymphocytes (CTL) provides a promising approach to the immunotherapy of cancer. A phase
I study was conducted to test the feasibility, safety, and survival of adoptively transferred
Melan-A–specific CTL lines in melanoma patients.
Purpose
The adoptive transfer of in vitro generated tumor antigen-specific cytotoxic T lymphocytes (CTL) provides a promising approach to the immunotherapy of cancer. A phase I study was conducted to test the feasibility, safety, and survival of adoptively transferred Melan-A–specific CTL lines in melanoma patients.
Citeseer