Administration of N-Acetyl-D-mannosamine to Mammals
SM Amir, SA Barker, WR Butt, AC Crooke, AG Davies - Nature, 1966 - nature.com
SM Amir, SA Barker, WR Butt, AC Crooke, AG Davies
Nature, 1966•nature.comAbstract N-ACETYL-d-mannosamine (NAM) is biochemically related to N-acetyl-d-
neuraminic acid (NANA), a constituent of both human follicle stimulating hormone and
human chorionic gonadotrophin (HCG). The compound itself is devoid of biological activity,
but when mixed with HCG it reduces the activity of this hormone in both the uterine weight
and ovulation assays1. We therefore considered it to be of interest to study the fate of NAM
after the administration of it to mammals.
neuraminic acid (NANA), a constituent of both human follicle stimulating hormone and
human chorionic gonadotrophin (HCG). The compound itself is devoid of biological activity,
but when mixed with HCG it reduces the activity of this hormone in both the uterine weight
and ovulation assays1. We therefore considered it to be of interest to study the fate of NAM
after the administration of it to mammals.
Abstract
N-ACETYL-D-mannosamine (NAM) is biochemically related to N-acetyl-D-neuraminic acid (NANA), a constituent of both human follicle stimulating hormone and human chorionic gonadotrophin (HCG). The compound itself is devoid of biological activity, but when mixed with HCG it reduces the activity of this hormone in both the uterine weight and ovulation assays1. We therefore considered it to be of interest to study the fate of NAM after the administration of it to mammals.
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