Signal transduction from multiple Ras effectors
ME Katz, F McCormick - Current opinion in genetics & development, 1997 - Elsevier
ME Katz, F McCormick
Current opinion in genetics & development, 1997•ElsevierRas proteins activate a signaling cascade through direct binding of the serine/threonine
kinase Raf. They also activate additional signaling pathways that are essential for full
biological activity. Candidate effectors for these pathways include the RalGDS and
phosphatidyl inositol 3′ kinase, as well as several other Ras binding proteins the
biochemical and biological properties of which are poorly understood.
kinase Raf. They also activate additional signaling pathways that are essential for full
biological activity. Candidate effectors for these pathways include the RalGDS and
phosphatidyl inositol 3′ kinase, as well as several other Ras binding proteins the
biochemical and biological properties of which are poorly understood.
Ras proteins activate a signaling cascade through direct binding of the serine/threonine kinase Raf. They also activate additional signaling pathways that are essential for full biological activity. Candidate effectors for these pathways include the RalGDS and phosphatidyl inositol 3′ kinase, as well as several other Ras binding proteins the biochemical and biological properties of which are poorly understood.
Elsevier
