[HTML][HTML] α-Tocopherol protects against diet induced atherosclerosis in New Zealand white rabbits

DC Schwenke, LL Rudel, MG Sorci-Thomas… - Journal of lipid …, 2002 - ASBMB
In this study, we asked the question" does α-tocopherol supplementation prevent an
increase in total plasma cholesterol (TPC) concentration and reduce the deposition of
cholesterol in arterial plaques of rabbits fed atherogenic diets?" Isocaloric diets containing
0.1% cholesterol to induce atherosclerosis were enriched in one of three fats: saturated fats
(SAT), monounsaturated fats (MONO), or n-6 polyunsaturated fats (POLY). Half of each of
the three diets were supplemented with 2,500 IU α-tocopherol/kg-diet. Unsupplemented …