Limb-girdle muscular dystrophy 2C: clinical aspects
MB Hamida, CB Hamida, M Zouari, S Belal… - Neuromuscular …, 1996 - Elsevier
The LGMD2C linked to chromosome 13q and related to a 35 KDa dystrophin-associated
glycoprotein deficiency, is very similar to Duchenne muscular dystrophy with an autosomal
recessive inheritance. It is characterized by a variability of the age of onset, the severity of
the evolution and the severity of myopathic changes at the muscle biopsy. This variability
was also present in the expression of the α-sarcoglycan between the same sibships and
between different families.
glycoprotein deficiency, is very similar to Duchenne muscular dystrophy with an autosomal
recessive inheritance. It is characterized by a variability of the age of onset, the severity of
the evolution and the severity of myopathic changes at the muscle biopsy. This variability
was also present in the expression of the α-sarcoglycan between the same sibships and
between different families.