Cell differentiation lineage in the prostate

Y Wang, SW Hayward, M Cao, KA Thayer, GR Cunha - Differentiation, 2001 - Elsevier
Prostatic epithelium consists mainly of luminal and basal cells, which are presumed to
differentiate from common progenitor/stem cells. We hypothesize that progenitor/stem cells
are highly concentrated in the embryonic urogenital sinus epithelium from which prostatic
epithelial buds develop. We further hypothesize that these epithelial progenitor/stem cells
are also present within the basal compartment of adult prostatic epithelium and that the
spectrum of differentiation markers of embryonic and adult progenitor/stem cells will be …