Fc receptors
JV Ravetch, JP Kinet - Annual review of immunology, 1991 - annualreviews.org
I The DeWitt Wallace Research Laboratories, Sloan-Kettering Institute for Cancer Research,
1275 York Avenue, New York, New York 10021; 2 Molecular Allergy and Immunology
Section, National Institute Allergy and Infectious Diseases, National Institutes of Health,
12441 Parklawn Drive, Rockville, Maryland 20852
1275 York Avenue, New York, New York 10021; 2 Molecular Allergy and Immunology
Section, National Institute Allergy and Infectious Diseases, National Institutes of Health,
12441 Parklawn Drive, Rockville, Maryland 20852
IgG fc receptors
JV Ravetch, S Bolland - Annual review of immunology, 2001 - annualreviews.org
Since the description of the first mouse knockout for an IgG Fc receptor seven years ago,
considerable progress has been made in defining the in vivo functions of these receptors in
diverse biological systems. The role of activating FcγRs in providing a critical link between
ligands and effector cells in type II and type III inflammation is now well established and has
led to a fundamental revision of the significance of these receptors in initiating cellular
responses in host defense, in determining the efficacy of therapeutic antibodies, and in …
considerable progress has been made in defining the in vivo functions of these receptors in
diverse biological systems. The role of activating FcγRs in providing a critical link between
ligands and effector cells in type II and type III inflammation is now well established and has
led to a fundamental revision of the significance of these receptors in initiating cellular
responses in host defense, in determining the efficacy of therapeutic antibodies, and in …