[HTML][HTML] Leptin and body weight regulation in patients with anorexia nervosa before and during weight recovery1–2

V Haas, S Onur, T Paul, DO Nutzinger… - The American journal of …, 2005 - Elsevier
Background: Leptin has been considered a starvation hormone, but its role in malnourished
patients is unknown. Objective: We aimed to characterize the role of leptin in metabolic
adaptation in women with anorexia nervosa (AN). Design: In a cross-sectional study, 57
women with AN [mean (±SD) body mass index (kg/m 2) on admission: 15.2±1.5] were
compared with 49 healthy, normal-weight women (mean body mass index: 22.3±2.3).
Nineteen patients were reinvestigated during weight gain 43 and 84 d after baseline. We …