Role of platelets in the development of atherosclerosis

Y Huo, KF Ley - Trends in cardiovascular medicine, 2004 - Elsevier
Platelets are blood cell fragments that originate from the cytoplasm of megakaryocytes in the
bone marrow and circulate in blood to play a major role in the hemostatic process and in
thrombus formation after an endothelial injury. Recent studies have provided insight into
platelet functions in inflammation and atherosclerosis. A range of molecules, present on the
platelet surface and/or stored in platelet granules, contributes to the cross-talk of platelets
with other inflammatory cells during the vascular inflammation involved in the development …