A novel approach for comparative study of periosteum, muscle, subcutis, and skin microcirculation by intravital fluorescence microscopy

M Rücker, F Roesken, B Vollmar, MD Menger - Microvascular research, 1998 - Elsevier
Herein, we report a new model, which allows comparative study of the microcirculation of
different peripheral tissues, ie, periosteum, skeletal muscle, subcutis, and skin. Using
dextran-insensitive Wistar rats gracilis and semitendinosus muscles of the left hindlimb were
prepared in association with their appertaining tibial fragments, subcutis, and skin. Blood
supply was guaranteed by the femoral artery via the saphenous vessels. High-resolution
intravital epi-illumination microscopy of the two muscles displayed the typical microvascular …