An electron microscope study of the megacaryocyte of the rat bone marrow: I. The development of the demarcation membrane system and the platelet surface coat

O Behnke - Journal of ultrastructure research, 1968 - Elsevier
The origin and development of the demarcation membrane system (DMS) were studied in
rat megacaryocytes using various approaches. For morphological studies whole-body
perfusion-fixation was used. Horse radish peroxidase and Thorotrast injected intravenously
showed that these substances passed into the DMS under in vivo conditions at all stages of
DMS development. Staining during fixation of megacaryocytes with ruthenium red or
lanthanum ions showed that these substances passed into the cavities of the DMS and …