Severe herpes virus (HSV-2) infection in two patients with myelodysplasia and undetectable NK cells and plasmacytoid dendritic cells in the blood

A Dalloul, E Oksenhendler, O Chosidow… - Journal of clinical …, 2004 - Elsevier
Background: How the immune system contains herpes simplex virus (HSV) infections is
partly understood. T cells from infected persons proliferate in response to HSV antigens in
vitro and may control local relapse rather than primary infection. NK cells have been
involved in the control of experimental infections. A potentially important, as yet unexplored,
population of interest might be the plasmacytoid dendritic cells (PDC), which contrary to
monocytes, produce very high amounts of the major antiviral molecules, type-I interferon …