Affinity maturation in ectopic germinal centers
BA De Boer, I Voigt, HJ Kim, SA Camacho… - … : Proceedings of the …, 2000 - Springer
Lymphoid Organogenesis: Proceedings of the Workshop held at the Basel …, 2000•Springer
It is becoming clear that a precisely structured lymphoid tissue is essential for the
establishment of an antigen specific immune response. The differentiation of the antigen
activated lymphocyte into effector cells requires a well organized microenvironment in which
the antigen specific and the antigen presenting cells come into close physical contact. The
central role of cytokines in lymphoid organogenesis and the important function of
chemokines for guided cell movement into and within the secondary lymphoid organs are …
establishment of an antigen specific immune response. The differentiation of the antigen
activated lymphocyte into effector cells requires a well organized microenvironment in which
the antigen specific and the antigen presenting cells come into close physical contact. The
central role of cytokines in lymphoid organogenesis and the important function of
chemokines for guided cell movement into and within the secondary lymphoid organs are …
Abstract
It is becoming clear that a precisely structured lymphoid tissue is essential for the establishment of an antigen specific immune response. The differentiation of the antigen activated lymphocyte into effector cells requires a well organized microenvironment in which the antigen specific and the antigen presenting cells come into close physical contact. The central role of cytokines in lymphoid organogenesis and the important function of chemokines for guided cell movement into and within the secondary lymphoid organs are just emerging.
Springer