A mutation in Bruton's tyrosine kinase as a cause of selective anti-polysaccharide antibody deficiency
PMD Wood, A Mayne, H Joyce, CIE Smith… - The Journal of …, 2001 - Elsevier
PMD Wood, A Mayne, H Joyce, CIE Smith, DM Granoff, DS Kumararatne
The Journal of pediatrics, 2001•ElsevierChildren and adults can have recurrent infection with invasive encapsulated bacterial
pathogens such as Streptococcus pneumoniae as a result of a selective inability to respond
to polysaccharide antigens. We have identified a mutation in the gene encoding Bruton's
tyrosine kinase in a male patient with selective anti-polysaccharide antibody deficiency.(J
Pediatr 2001; 139: 148-51)
pathogens such as Streptococcus pneumoniae as a result of a selective inability to respond
to polysaccharide antigens. We have identified a mutation in the gene encoding Bruton's
tyrosine kinase in a male patient with selective anti-polysaccharide antibody deficiency.(J
Pediatr 2001; 139: 148-51)
Children and adults can have recurrent infection with invasive encapsulated bacterial pathogens such as Streptococcus pneumoniae as a result of a selective inability to respond to polysaccharide antigens. We have identified a mutation in the gene encoding Bruton’s tyrosine kinase in a male patient with selective anti-polysaccharide antibody deficiency. (J Pediatr 2001;139:148-51)
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