[HTML][HTML] Distinct antitumor properties of a type IV collagen domain derived from basement membrane
Y Maeshima, PC Colorado, A Torre… - Journal of Biological …, 2000 - ASBMB
Vascular basement membrane is an important structural component of blood vessels.
During angiogenesis this membrane undergoes many alterations and these changes are
speculated to influence the formation of new capillaries. Type IV collagen is a major
component of vascular basement membrane, and recently we identified a fragment of type
IV collagen α2 chain with specific anti-angiogenic properties (Kamphaus, GD, Colorado, PC,
Panka, DJ, Hopfer, H., Ramchandran, R., Torre, A., Maeshima, Y., Mier, JW, Sukhatme, VP …
During angiogenesis this membrane undergoes many alterations and these changes are
speculated to influence the formation of new capillaries. Type IV collagen is a major
component of vascular basement membrane, and recently we identified a fragment of type
IV collagen α2 chain with specific anti-angiogenic properties (Kamphaus, GD, Colorado, PC,
Panka, DJ, Hopfer, H., Ramchandran, R., Torre, A., Maeshima, Y., Mier, JW, Sukhatme, VP …