Basal linear deposit and large drusen are specific for early age-related maculopathy

CA Curcio, CL Millican - Archives of ophthalmology, 1999 - jamanetwork.com
Objective To determine the distributions of basal laminar and basal linear deposits in Bruch
membrane (BM) with respect to age and early age-related maculopathy (ARM). Methods
The foveas of 41 human eyes (< 60 years [n= 9];≥ 60 years [n= 32]), preserved no later than
3.5 hours post mortem, were examined using light and electron microscopy. Ten eyes met
histopathologic criteria of the Alabama Age-related Macular Degeneration Grading System
for early ARM. We calculated the specificity, sensitivity, and odds ratios for the association of …