Increases in sucrose consumption, but not ethanol consumption, following ICV NPY administration
CJ Slawecki, M Betancourt, T Walpole… - Pharmacology …, 2000 - Elsevier
Neuropeptide Y (NPY) is a centrally acting neuromodulator that influences both
consummatory behaviors and anxiety. NPY's effects on feeding are primarily regulated
through Y5 receptors in hypothalamic sites, whereas NPY-induced anxiolysis appears to be
mediated by Y1 receptors in the amygdala. Recently, NPY has been postulated to play a
role in the regulation of ethanol consumption. The present study assessed the influence of
intracerebroventricular (ICV) administration of NPY on the consumption of 10% ethanol or …
consummatory behaviors and anxiety. NPY's effects on feeding are primarily regulated
through Y5 receptors in hypothalamic sites, whereas NPY-induced anxiolysis appears to be
mediated by Y1 receptors in the amygdala. Recently, NPY has been postulated to play a
role in the regulation of ethanol consumption. The present study assessed the influence of
intracerebroventricular (ICV) administration of NPY on the consumption of 10% ethanol or …