Low Blood CD8+ T-Lymphocytes and High Circulating Monocytes Are Predictors of HIV-1-Associated Progressive Encephalopathy in Children
S Sánchez-Ramón, J Mͣ Bellón, S Resino… - …, 2003 - publications.aap.org
Objective. Human immunodeficiency virus type 1 (HIV-1)-associated progressive
encephalopathy (PE) is a common and devastating complication of HIV-1 infection in
children, whose risk factors have not yet been clearly defined. Regardless of the age of
presentation, PE shortens life expectancy. Paradoxically, as survival of patients has been
prolonged as a result of the use of antiretroviral therapy, the prevalence of PE has
increased. Therefore, a predictive marker of PE emergence is critical. The objective of this …
encephalopathy (PE) is a common and devastating complication of HIV-1 infection in
children, whose risk factors have not yet been clearly defined. Regardless of the age of
presentation, PE shortens life expectancy. Paradoxically, as survival of patients has been
prolonged as a result of the use of antiretroviral therapy, the prevalence of PE has
increased. Therefore, a predictive marker of PE emergence is critical. The objective of this …