Prevention of group B streptococcal colonization with topically applied lipoteichoic acid in a maternal-newborn mouse model
F Cox - Pediatric research, 1982 - nature.com
F Cox
Pediatric research, 1982•nature.comAn animal model of maternal-newborn transmission of group B streptococci (GBS) was
developed. Pregnant Swiss-Webster mice were colonized by applying 10 8 GBS to the oral
cavity, vagina, and nipples daily for 3 days before delivery. Lipoteichoic acid (LTA) from type
III GBS or phosphate buffered saline was applied topically to the oral cavity, perineum or
nape of newborn mice.
developed. Pregnant Swiss-Webster mice were colonized by applying 10 8 GBS to the oral
cavity, vagina, and nipples daily for 3 days before delivery. Lipoteichoic acid (LTA) from type
III GBS or phosphate buffered saline was applied topically to the oral cavity, perineum or
nape of newborn mice.
Abstract
An animal model of maternal-newborn transmission of group B streptococci (GBS) was developed. Pregnant Swiss-Webster mice were colonized by applying 10 8 GBS to the oral cavity, vagina, and nipples daily for 3 days before delivery. Lipoteichoic acid (LTA) from type III GBS or phosphate buffered saline was applied topically to the oral cavity, perineum or nape of newborn mice.
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