Tissue distribution of mammalian aldose reductase and related enzymes

HB Markus, M Raducha, H Harris - Biochemical medicine, 1983 - Elsevier
Activities of aldose reductase (AR) and related NADPH-dependent enzymes were examined
in extracts of human, cat, dog, guinea pig, mouse, monkey, pig, rabbit, rat and sheep lenses
and a variety of other tissues. The activity of the tissues against dl-glyceraldehyde, d-
glucuronic acid, and 3-pyridinecarboxaldehyde (PCA) was determined. High
glyceraldehyde: glucuronic acid activity ratios, a characteristic of aldose reductase, were
found in all lenses, except from mouse. An analytical thin-layer isoelectric focusing system …