Response properties of high-threshold cutaneous cold receptors in the primate

RH LaMotte, JG Thalhammer - Brain research, 1982 - Elsevier
RH LaMotte, JG Thalhammer
Brain research, 1982Elsevier
Cutaneous high-threshold cold receptors (HCRs) in the monkey were identified as sensitive
only to cold temperatures below 27° C and not responsive to mechanical or heat noxious
stimulation. Some HCRs had axons conducting in the low A-δ range while others had C
fibers. The response properties of HCRs were contrasted with those of mechanothermal
nociceptors, the latter believed to contribute to the sense of cold pain. HCRs with Aδ fibers
may contribute to the sense of innocuous cold below temperatures to which low-threshold …
Abstract
Cutaneous high-threshold cold receptors (HCRs) in the monkey were identified as sensitive only to cold temperatures below 27°C and not responsive to mechanical or heat noxious stimulation. Some HCRs had axons conducting in the low A-δ range while others had C fibers. The response properties of HCRs were contrasted with those of mechanothermal nociceptors, the latter believed to contribute to the sense of cold pain. HCRs with Aδ fibers may contribute to the sense of innocuous cold below temperatures to which low-threshold cold receptors are maximally responsive.
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