Hematologic manifestations associated with deletions of the long arm of chromosome 20
MP Davis, GW Dewald, RV Pierre… - Cancer genetics and …, 1984 - Elsevier
We investigated 20 patients with hematologic disorders who had a clone of cells with a
deletion of most of a chromosome# 20 long arm (20q−) in the bone marrow. Three patients
had polycythemia vera (PV), 6 had acute nonlymphocytic leukemia (ANLL), 8 had
preleukemia (PL), and 3 had other myeloproliferative disorders. In our laboratory, a 20q−
chromosome is found in 6% of patients with PV, 3% of patients with ANLL, and 1% of
patients with PL. Among the 6 patients with ANLL and a 20q− abnormality, 3 had …
deletion of most of a chromosome# 20 long arm (20q−) in the bone marrow. Three patients
had polycythemia vera (PV), 6 had acute nonlymphocytic leukemia (ANLL), 8 had
preleukemia (PL), and 3 had other myeloproliferative disorders. In our laboratory, a 20q−
chromosome is found in 6% of patients with PV, 3% of patients with ANLL, and 1% of
patients with PL. Among the 6 patients with ANLL and a 20q− abnormality, 3 had …