Pathophysiology of viral myocarditis: the role of humoral immune response
The pathophysiology of viral myocarditis is still a matter of debate. Humoral autoimmunity in
postviral heart disease remains an attractive but complex hypothesis. Antigenic mimicry with
or without cytolytic antibody properties has been shown to play a role in the
immunopathogenesis of myocarditis with respect to sarcolemmal/myolemmal epitopes
(including the beta-receptor), myosin and some mitochondrial proteins including the
antinucleotide translocator (ANT)-carrier and dihydrolipoamid dehydrogenase. Today …
postviral heart disease remains an attractive but complex hypothesis. Antigenic mimicry with
or without cytolytic antibody properties has been shown to play a role in the
immunopathogenesis of myocarditis with respect to sarcolemmal/myolemmal epitopes
(including the beta-receptor), myosin and some mitochondrial proteins including the
antinucleotide translocator (ANT)-carrier and dihydrolipoamid dehydrogenase. Today …