The ability to localize mRNA transcripts on histological sections in situ is one of the most
satisfying procedures for the cell biologist and embryologist. The field of molecular
embryology has been revolutionized by the rapidity with which newly isolated genes can be
characterized by their localization on single embryo tissue sections. It is astonishing how
many sophisticated laboratories still consider this technique to be an obstacle despite its
high visibility in the current literature. Many protocols are unreliable, incomplete, or …